两者之间应该是有一些交集的,既然都做了建议你选择g:profiler结果,相对于DAVID来说,g:profiler数据库更新一些
老师,你好,我用DAVID和g:Profiler两个软件做GO富集分析,得到的结果完全不同,是做错了吗,还是不同的软件结果就应该不同呢?如果不同软件得出的富集结果就应该不同,那么应该怎么取舍,选择什么样的结果来用在发表文章中呢?请老师指导一下,谢谢。
用 DAVID做的结果是
GO:0008015 GO Biological Processes blood circulation GO:0006936 GO Biological Processes muscle contraction GO:0008038 GO Biological Processes neuron recognition GO:0060485 GO Biological Processes mesenchyme development GO:0003300 GO Biological Processes cardiac muscle hypertrophy 用g:Profiler做的结果是 GO:0014910 GO Biological Processes regulation of smooth muscle cell migration GO:0071229 GO Biological Processes cellular response to acid chemical GO:0071363 GO Biological Processes cellular response to growth factor stimulus GO:0000904 GO Biological Processes cell morphogenesis involved in differentiation GO:0010035 GO Biological Processes response to inorganic substance