CIBERSORT是一个网络在线工具用于计算免疫浸润,可以自己去用数据库。
附上网址:
https://cibersort.stanford.edu/
老师您好,
我是药理学研究生,在文献研究中有关于“通过对TCGA中膀胱癌患者的RNA-seq数据进行CIBERSORT方法测算,以确定肿瘤浸润型免疫细胞群体的相对丰度”的图,我查了很多相关资料,仍然不解。希望老师有时间能帮我解答一下,感谢!
(G) Relative abundance of tumor-infiltrating immune cell populations determined by the CIBERSORT methodology (24) in bladder cancer patients from RNA-seq data in TCGA (n = 433) as a function of DDR2 expression. ***P < 0.001, ****P < 0.0001.
以及附录里的补充图:
Fig. S6. Quantification of immune cell populations in bladder cancer patients with varying DDR2 expression levels. (A), Distribution of DDR2 expression in quartiles. (B), Relative abundance of tumor-infiltrating immune cell populations determined by CIBERSORT methodology (24) in bladder cancer patients from RNAseq data in the TCGA (n = 433).
*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.
原文献: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382401/